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Patients with LARC who received neoadjuvant chemoradiation between September 2007 and December 2012 were retrospectively reviewed. Neoadjuvant therapy comprised 5-fluorouracil/cisplatin or capecitabine/oxaliplatin with or without bevacizumab. Patients without downstaging achieved by the therapy underwent surgery; those without were offered additional chemoradiotherapy. Perioperative data, pathological and oncological outcomes, and survival were compared between the patients who received surgery (Group S) and those who did not (Group C). Neoadjuvant therapy was given to 90 patients; 36 patients (40 %) underwent surgery. Lymph node metastasis was noted in 16 patients (44.4 %) in Group S and in 10 patients (27.8 %) in Group C (p = 0.080). There were no significant differences in adverse events, pathological complete response, and overall survival. In multivariate analysis, number of organ metastasis, and adjuvant chemotherapy were independent prognostic factors for cancer-specific survival (hazard ratio (HR) 2.1, p = 0.04; and HR 3.8, p = 0.01, respectively). Of the 36 patients who underwent surgery, 1 patient was found to have a recurrent cancer 8 years after the operation. The outcome of LARC patients who received neoadjuvant chemoradiation and achieved downstaging was better than that of patients who did not. Furthermore, chemoradiotherapy and subsequent surgery were both independent prognostic factors.How will the healthy couple survive a global pandemic? Couple’ Smart Recovery Crack Keygen For (LifeTime) [April-2022] 1a423ce670 Smart Recovery Crack FluxBB, a forum software and development platform, is a free and open source forum solution. It is known for its fast and clean-looking interface, easy to use and is able to handle over 100,000 concurrent users. 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